Isolation of Phaffia rhodozyma auxotrophic mutants by enrichment methods.

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Selection of Astaxanthin-Overproducing Mutants of Phaffia rhodozyma with beta-Ionone.

beta-Ionone, an end ring analog of beta-carotene, inhibits astaxanthin production in the red yeast Phaffia rhodozyma. Astaxanthin-overproducing mutants of this yeast are easily spotted on beta-ionone-containing yeast malt agar plates. beta-Ionone appears to block astaxanthin synthesis at the beta-carotene level.

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Astaxanthin production by Phaffia rhodozyma using a pH-stat control

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Minimal medium for isolation of auxotrophic Zymomonas mutants.

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Isolation and characterization of mutants of Saccharomyces cerevisiae auxotrophic and conditionally auxotrophic for 5'-dTMP.

An improved method for isolation of yeast m utants auxotrophic for 5'-dTM P is presented. The procedure employs the two folic acid antagonists aminopterin and sulfanilamide (SA A). Selec­ tiveness of the procedure depends on concentration of SAA and time of incubation. 44 mutants auxotrophic and 3 conditionally auxotrophic for 5'-dTMP were isolated. All belong to one complementation group. The ...

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Impact of gamma rays on the Phaffia rhodozyma genome revealed by RAPD-PCR

BACKGROUND AND OBJECTIVES Phaffia rhodozyma is a red yeast which produces astaxanthin as the major carotenoid pigment. Astaxanthin is thought to reduce the incidence of cancer and degenerative diseases in man. It also enhances the immune response and acts as a free-radical quencher, a precursor of vitamin A, or a pigment involved in the visual attraction of animals as mating partners. The impac...

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ژورنال

عنوان ژورنال: The Journal of General and Applied Microbiology

سال: 1993

ISSN: 1349-8037,0022-1260

DOI: 10.2323/jgam.39.303